Dosage form :


Doses :

10/15/25 mg

Short Description:

Enlido contains the active substance "lenalidomide". This medicine belongs to a group of medicines which affect how your immune system works

Product Introduction

What Enlido is and what it is used for

The active ingredient of this medicine is Lenalidomide. Enlido belongs to a group of medicines, which affect how your immune system works.

Enlido is used in adults for:

  • Multiple myeloma
  • Myelodysplastic syndromes
  • Mantle cell lymphoma
  • Follicular lymphoma

Multiple myeloma

Multiple myeloma is a type of cancer, which affects a certain kind of white blood cell, called the plasma cell. These cells collect in the bone marrow and divide, becoming out of control. This can damage the bones and kidneys. Multiple myeloma generally cannot be cured. However, the signs and symptoms can be greatly reduced or disappear for a period of time; this is called a ‘response’. Newly diagnosed multiple myeloma; in patients who have had a bone marrow transplant Enlido is used on its own as a maintenance therapy after patients have recovered enough following a bone marrow transplant.

Newly diagnosed multiple myeloma; in patients who cannot have a bone marrow transplant Enlido is taken with other medicines. These may include:

  • a chemotherapy medicine called ‘Bortezomib’
  • an anti-inflammatory medicine called ‘Dexamethasone’
  • a chemotherapy medicine called ‘Melphalan’ and• an immunosuppressant medicine called ‘Prednisone’.

You will take these other medicines at the start of treatment and then continue to take Enlido on its own.

If you are aged 75 years or older or have moderate to sever kidney problems, your doctor will check you carefully before starting treatment.

Multiple myeloma; in patients who have had treatment before

Enlido is taken together with an anti-inflammatory medicine called ‘Dexamethasone’.

Enlido can stop the signs and symptoms of multiple myeloma getting worse. It has also been shown to delay multiple myeloma from coming back following treatment.

Myelodysplastic syndromes (MDS)

Myelodysplastic syndromes are a collection of many different blood and bone marrow diseases. The blood cells become abnormal and do not function properly. Patients can experience a variety of signs and symptoms including a low red blood cell count (anemia), the need for a blood transfusion, and be at risk of infection.

Enlido is used alone to treat adult patients who have been diagnosed with MDS, when all of the following apply:

  • you need regular blood transfusions to treat low levels of red blood cells (‘transfusion-dependent anemia’)• you have an abnormality of cells in the bone marrow called an ‘isolated deletion 5q cytogenetic abnormality’. This means your body does not make enough healthy blood cells
  • other treatments have been used before, are not suitable or do not work well enough

Enlido can increase the number of healthy red blood cells that the body produces by reducing the number of abnormal cells:

  • this can reduce the number of blood transfusions needed. It is possible that no transfusions will be needed.

Mantle cell lymphoma (MCL)

Mantle cell lymphoma is a cancer of part of the immune system (the lymph tissue). It affects a type of white blood cell called B-lymphocytes or B-cells. MCL is a disease where B-cells grow in an uncontrolled way and build up in the lymph tissue, bone marrow or blood.

Enlido is used alone to treat adult patients who have previously been treated with other medicines.

Follicular lymphoma (FL)

Follicular lymphoma is a slow growing cancer that affects the B-lymphocytes, the type of white blood cells that help your body fight infection. When you have FL, too many of these B-lymphocytes may collect in your blood, bone marrow, lymph nodes and spleen.

Enlido is taken together with another medicine called ‘Rituximab’ for the treatment of adult patients with previously treated follicular lymphoma.

How Enlido works

Enlido works by affecting the body’s immune system and directly attacking the cancer cells. It works in a number of different ways: • By stopping the cancer cells developing

  • By stopping blood vessels growing in the cancer
  • By stimulating part of the immune system to attack the cancer cells











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