Before you take Imatinib ACTe
Imatinib ACTe will only be prescribed to you by a doctor with experience in medicines to treat blood cancers or solid tumors. Follow all your doctor’s instructions carefully, even if they differ from the general information contained in this leaflet.
Do not take Imatinib ACTe
- If you are allergic to imatinib or any of the other ingredients of this medicine (listed insection 6).
If this applies to you, tell your doctor without taking Imatinib ACTe.
If you think you may be allergic but are not sure, ask your doctor for advice.
Warnings and precautions
Talk to your doctor before taking Imatinib ACTe:
- If you have or have ever had a liver, kidney or heart problem.
- If you are taking the medicine levothyroxine because your thyroid has been removed.
If you have ever had or might now have a hepatitis b infection. This is because Imatinib ACTe could cause hepatitis b to become active again,
which can be fatal in some cases. Patients will be carefully checked by their doctor for signs of this infection before treatment is started.
- If you experience bruising, bleeding, fever, fatigue and confusion when taking Imatinib ACTe, contact your doctor. This may be a sign of damage to blood vessels known as thrombotic microangiopathy (TMA).
If any of these apply to you, tell your doctor before taking Imatinib ACTe.
You may become more sensitive to the sun while taking Imatinib ACTe. It is important to cover sun-exposed areas of skin and use sunscreen with high sun protection factor (SPF). These precautions are also applicable to children.
During treatment with Imatinib ACTe, tell your doctor straight away if you put on weight very quickly.
Imatinib ACTe may cause your body to retain water (severe fluid retention). While you are taking Imatinib ACTe, your doctor will regularly check whether the medicine is working. You will also have blood tests and be weighed regularly.
Children and adolescents
Imatinib ACTe is also a treatment for children with CML. There is no experience in children with CML below 2 years of age. There is limited experience in children with Ph-positive ALL and very limited experience in children with MDS/MPD, DFSP, GIST and HES/CEL.
Some children and adolescents taking Imatinib ACTe may have slower than normal growth. The doctor will monitor the growth at regular visits.
Other medicines and Imatinib ACTe
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription (such as paracetamol) and including herbal medicines (such as
St. John’s Wort). Some medicines can interfere with the effect of Imatinib
ACTe when taken together. They may increase or decrease the effect of
Imatinib ACTe, either leading to increased side effects or making Imatinib ACTe less effective. Imatinib ACTe may do the same to some other medicines.
Tell your doctor if you are using medicines that prevent the formation of blood clots.
Pregnancy, breast-feeding and fertility
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine.
Imatinib ACTe is not recommended during pregnancy unless clearly necessary as it may harm your baby. Your doctor will discuss with you the possible risks of taking Imatinib ACTe during pregnancy. Women who might become pregnant are advised to use effective contraception during treatment.
Do not breast-feed during the treatment with Imatinib ACTe.
Patients who are concerned about their fertility while taking Imatinib ACTe are advised to consult with their doctor.
Driving and using machines
You may feel dizzy or drowsy or get blurred vision while taking this medicine. If this happens, do not drive or use any tools or machines until you are feeling well again.