Tinlo

Erlotinib

Chemical

Oral

Dosage form :

Tablets

Doses :

150 mg

Short Description:

Tinlo contains the active substance erlotinib. Tinlo is a medicine used to treat cancer by preventing the activity of a protein called epidermal growth factor receptor (EGFR).

Product Introduction

What Tinlo is and what it is used for?

Tinlo contains the active substance Erlotinib. Tinlo is a medicine used to treat cancer by preventing the activity of a protein called epidermal growth factor receptor (EGFR). This protein is known to be involved in the growth and spread of cancer cells.

Tinlo is indicated for adults. This medicine can be prescribed to you if you have non-small cell lung cancer at an advanced stage. It can be prescribed as initial therapy or as therapy if your disease remains largely unchanged after initial chemotherapy, provided your cancer cells have specific EGFR mutations. It can also be prescribed if previous chemotherapy has not helped to stop your disease.

This medicine can also be prescribed to you in combination with another treatment called gemcitabine if you have cancer of the pancreas at a metastatic stage.

Before you take Tinlo

Do not take Tinlo

If you are allergic to Erlotinib or any of the ingredients of this medicine (listed in section 6).

Warnings and precautions:

Talk to your doctor or pharmacist before taking Tinlo.

Take special care with Tinlo:

If you are taking other medicines that may increase or decrease the amount of Erlotinib in your blood or influence its effect (for example antifungals like ketoconazole, protease inhibitors, erythromycin, clarithromycin, phenytoin, carbamazepine, barbiturates, rifampicin, ciprofloxacin, omeprazole, ranitidine, St. John’s Wort or proteasome inhibitors), talk to your doctor. In some cases these medicines may reduce the efficacy or increase the side effects of Tinlo and your doctor may need to adjust your treatment. Your doctor might avoid treating you with these medicines while you are receiving Tinlo.
If you are taking anticoagulants (a medicine which helps to prevent thrombosis or blood clotting E.g. Warfarin), Tinlo may increase your tendency to bleed. Talk to your doctor, he will need to regularly monitor you with some blood
If you are taking statins (medicines to lower your blood cholesterol), Tinlo may increase the risk of statin related muscle problems (unexplained muscle pain, tenderness, weakness or cramps), which on rare occasions can lead to serious muscle breakdown (rhabdomyolysis) resulting in kidney damage, talk to your
If you use contact lenses and/or have a history of eye problems such as severe dry eyes, inflammation of the front part of the eye (cornea) or ulcers involving the front part of the eye, tell your
If you have sudden difficulty in breathing associated with cough or fever because your doctor may need to treat you with other medicines and interrupt your Tinlo treatment;
If you have diarrhea because your doctor may need to treat you with anti-diarrheal (for example loperamide);
Immediately, if you have severe or persistent diarrhea, nausea, loss of appetite, or vomiting because your doctor may need to interrupt your Tinlo treatment and may need to treat you in the hospital;
If you have severe pain in the abdomen, severe blistering or peeling of skin. Your doctor may need to interrupt or stop your treatment;
If you develop acute or worsening redness and pain in the eye, increased eye watering, blurred vision and/or sensitivity to light, please tell your doctor or nurse immediately as you may need urgent treatment.
It is not known whether Tinlo has a different effect if your liver or kidneys are not functioning normally. The treatment with this medicine is not recommended if you have a severe liver disease or severe kidney
If you are treated with Tinlo, you are advised to stop smoking as smoking could decrease the amount of your medicine in the
Your doctor must treat you with caution if you have a glucuronidation disorder like Gilbert’s syndrome.

Children and adolescents

Tinlo has not been studied in patients under the age of 18 years. The treatment with this medicine is not recommended for children and adolescents.

Other medicines and Tinlo

Tell your doctor or pharmacist if you are taking, have recently taken any other medicines or might take any other medicines.

Pregnancy and breast-feeding

Avoid pregnancy while being treated with Tinlo. If you could become pregnant, use adequate contraception during treatment, and for at least 2 weeks after taking the last tablet.

If you become pregnant while you are being treated with Tinlo, immediately inform your doctor who will decide if the treatment should be continued.

Do not breast-feed if you are being treated with Tinlo, and for at least 2 weeks after taking the last tablet.

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Driving and using machines

Tinlo has not been studied for its possible effects on the ability to drive and use machines but it is very unlikely that your treatment will affect this ability.

Tinlo contains a sugar called lactose monohydrate

If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking Tinlo.

How to take Tinlo?

Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.

The tablet should be taken at least one hour before or two hours after the ingestion of food. Don’t take Tinlo with food.

The usual dose is one tablet of Erlotinib 150 mg each day if you have non-small cell lung cancer.

The usual dose is one tablet of Erlotinib 100 mg each day if you have metastatic pancreatic cancer. Tinlo is given in combination with gemcitabine treatment.

Your doctor may adjust your dose in 50 mg steps.

If you take more Tinlo than you should

Contact your doctor or pharmacist immediately. You may have increased side effects and your doctor may interrupt your treatment.

If you forget to take Tinlo

If you miss one or more doses of Tinlo, contact your doctor or pharmacist as soon as possible. Do not take a double dose to make up for a forgotten dose.

If you stop taking Tinlo

It is important to keep taking Tinlo every day, as long as your doctor prescribes it for you. If you have any further questions on the use of this medicine, ask your doctor or pharmacist.